Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKWLQIHITVDQEQVEFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQQDEQDPIDVDTLEAFLKAQLPDVPMRHEELEDQVWERAWMDYYEPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDVKNKIVIDYGCGSGILGVAALLLGAKKVYATDIDPQAVLATKQNAELNGVLDRLYVGLPEEFDQEFKPQQADVLVANILAGPLMALAPEFAKLLKSDGDFALAGVIEEQVVDVSGVYSEFFDILDVEKREENWCRISGKRKTTN 3CJQ Chain:G ((52-224)) ----------------------------------------------------------------------------------------EEVG--DWLEAWRRDLKP-ALAPPFVVLAPW-HTWEGAEIPLVIEPGMAFGTGHHETTRLALKALARHLRPGDKVLDLGTGSGVLAIAAEKLGGKAL-GVDIDPMVLPQAEANAKRNGVRPRFLEG-SLEAALPFGP--FDLLVANLYAELHAALAPRYREALVPGGRALLTGILKDRA----------------------------------

General information: TITO was launched using: RESULT: Template: 3CJQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 896 -72914 -81.38 -426.39 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain G : 0.67 3D Compatibility (PKB) : -81.38 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.408

(partial model without unconserved sides chains): PDB file : Tito_3CJQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CJQ-query.scw PDB file : Tito_Scwrl_3CJQ.pdb: