Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRFYSLYLHDDACKNRQNLSSCRTYSVSLEFESRRDNMSNENQKPTSPTEQAQSSDKVSPFLSSPLPQGTPQGQQQSLQQTLTDTPVSGSVPKYNLPRGAGNTGNVGETTHFGYSTVRTEDKAQKVAEVFHSVASKYDLMNDLMSFGIHRLWKRFAINM--SGVRRGQ----HVLDIAGGTGDLA-----KVFSREVGPQGHVVLSDINESMLNVGRDRLIDAGCT----NVDFVLANAETLEPFADNSFDLVTISFGLRNVTDKDAALASMFRVLKPGGRLLVLEFSKPVFEPFSKLYDLYSFTALPIMGKLVANDSESYKYLAESIRMHPDQRTLKGMMENAGFQNCDYHNLTGGIVAVHRGFKL 4OBW Chain:D ((23-257)) -----------------------------------------------------------------------------------------------------------------------------------SVANRYDLMNDVMSLGIHRLWKDHFINKLDAGKRPNSTTPLNFIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKRAMEQGKYFKDPRVRFLVSNGEKLEEIDSDSKDIYTVSFGIRNFTDIQKGLNTAYRVLKPGGIFYCLEFSK-IENPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFPDQETFKSMIEKAGFKSAGYESLTFGICAIHWGIKV

General information: TITO was launched using: RESULT: Template: 4OBW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 994 40204 40.45 182.75 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain D : 0.73 3D Compatibility (PKB) : 40.45 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_4OBW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OBW-query.scw PDB file : Tito_Scwrl_4OBW.pdb: