Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYDEECPIMANDNHNQVLDEHTEVVVEGDKASAKRARKVKPKTSDVGSTASLFGIAPYQPKKNEEYMSEGQLEHFRQILQTWKAELMSEVDRTLNTMQDESTALPDVNDRATQEEEFAIELRTRDRERKLIRKIEQSLEAIKNEDYGFCETCGIEIGLRRLEARPTATLCIDCKTLAEIKEKQNNG--- 3TOW Chain:A ((47-198)) -----------------MDPITGVGVVASRNRAPTGYDVVAQTAD-GVDADLWKDGLFKSKVT----------RYLCFTRS--------FSKENSHLGNVLVDMKLIDIKDTLPVGFIPIQETVDTQEVAFRK-KRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGHHHHHH

General information: TITO was launched using: RESULT: Template: 3TOW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 733 -22251 -30.36 -149.34 target 2D structure prediction score : 0.37 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -30.36 2D Compatibility (Sec. Struct. Predict.) : 0.37 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.107

(partial model without unconserved sides chains): PDB file : Tito_3TOW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TOW-query.scw PDB file : Tito_Scwrl_3TOW.pdb: