Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQYQMITREQCLYWDQEDELKKFKDEFALPEGVIYLDGNSLGARPKKSLAVAQHIISQEWGEDLINSWNKADWWGLPTRLGDKVAKLVGAEQGEVVISDSTTLNLFKVLSAAVKIQADKFPEHKIIVAEKDAFPTDIYIIEGFIDLIQKGYQVELID-------GVEDLSRALEKDVAVVVLSHVNYRTGYFYDMASINEQIHS--KDALVIWDLCHSVGAVPMHLNQTDSDFAIGCTYKYLNGGPGSPALLWVNEKHRDQFWQPLSGWWSHKKPFDMAQHYEPANSIRRYLCGTQPVISMSLIECGVDIFLHADMQKIREKSLKLTDLFIQLVHQECSEFGFELITPLDHKHRGSHVSYRHEFGYEIIQALIARGV-----------IGDYREPAVLRFGITPLYLGFEDIWNAVQHLKATMLNSEWKNKEYLVRGEVT 1ECX Chain:A ((1-376)) MR-------------------------------VYFDNNATTRVDDRVLEEMIVFYREKYGNPNSAHGMGIEANLHMEKAREKVAKVLGVSPSEIFFTSCATESINWILKTVAETFEKR--KRTIITTPIE----HKAVLETMKYLSMKGFKVKYVPVDSRGVVKLEELEKLVDEDTFLVSIMAANNEVGTIQPVEDVTRIVKKKNKETLVHVDAVQTIGKIPFSLEKLEVDYASFSAHKF--HGPKGVGITYI------------------RKGVPIRPLIHGGGQERGLRSGTQNVPGIVGAARAMEIAVE-ELSEAAKHMEKLRSKLVSGLMNLGAHIITPLEISLPN---TLSVSFPNIRGSTLQNLLSGYGIYVSTHVLDAMGVDRRIAQGAIRISLCK-YNTEEEVDYFLKKIEEILSFL--------------

General information: TITO was launched using: RESULT: Template: 1ECX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1951 -9722 -4.98 -28.26 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -4.98 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_1ECX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ECX-query.scw PDB file : Tito_Scwrl_1ECX.pdb: