Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDFDFNLILVPVTLILFAVWLLDKLVFKQRANKGRENENFVITWAYDFWPVLAVVLVLRSFTYEPFNIPSDSMVPTLETGDFILVNKFDYGVRLPIVNKKVIDVGEPKRGDVIVFRYPPQPTISYIKRVIGLPGDHIVYD--HGQLII-----NGQKIP-KVPTQFS--REKDALDTPTSIYHKETIGDHTFTMREL-------EGVNVARQAPFINYVDN------------GKYANQDGLYWEV-TVPKGHYFAMGDNRDQSADSRFWGFVPEENLTGRAFYVWMHKEPGFHLPSFNRNGKID 3IIQ Chain:B ((6-227)) -------------------------------------------------------------IYEPFQIPSGSMMPTLLIGDFILVEKF---------------TGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDPVSKELTIQPGCSSG--CENALPVTYSNVEPSDFVQT----FSRRN---ATSGFFEVPKNETKENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNRDNSADSRYWGFVPEANLVGRATAIWM------------------

General information: TITO was launched using: RESULT: Template: 3IIQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 685 -9148 -13.35 -53.18 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -13.35 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_3IIQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IIQ-query.scw PDB file : Tito_Scwrl_3IIQ.pdb: