Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRMLHTMLRVGNLEQSLKFYTEVLGMKLLRKRDYEEGRFTLAFVGYGDEENNTMLELTHNWDTSSYDLGNGYGHIAIGVEDAYKACEEIKARGGKVVREAGPMKGGVTVIAFVEDPDGYKVELIQQDANARNN 4MTS Chain:B ((1-126)) MRILHSMLRVADLEAALEFYTRALDMRLLRRRDYPEGRFTLAFVGYQDERAAAALELTHNWDRDGYTQGDGYGHLAIEVEDAAVTCARARALGYRVTREAGLMQHGRSVIAFLEDPDGYKVELIQK-------

General information: TITO was launched using: RESULT: Template: 4MTS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 516 -56310 -109.13 -446.90 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.89 3D Compatibility (PKB) : -109.13 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.89 QMean score : 0.602

(partial model without unconserved sides chains): PDB file : Tito_4MTS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MTS-query.scw PDB file : Tito_Scwrl_4MTS.pdb: