Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRDRIMQITIRGHHLAITPAIEENIKAKFNQLTKHLDQVNSMQIKLTKDHQIDKRSHKGSSNHVAEAIVRLPGIELFAQATADDMYTSIKKLTEKLKKQLLKYRKMQCTYSQVAVSI----- 1IMU Chain:A ((1-107)) -----MTLNITSKQMDITPAIREHLEERLAKLGKWQTQLISPHFVLNKVPN----------GFSVEASIGTPLGNLLASATSDDMYKAINEVEEKLERQLNKLQHKSESRRADERLKDSFEN

General information: TITO was launched using: RESULT: Template: 1IMU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 429 -43242 -100.80 -423.94 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -100.80 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.445

(partial model without unconserved sides chains): PDB file : Tito_1IMU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IMU-query.scw PDB file : Tito_Scwrl_1IMU.pdb: