Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFHGFITRRVRPPLSVTHREAERLLEPKPQGCYLVRFSESA-VTFVLTYRSRTCCRHFLLAQLRD-----------------GRHVVLGEDSAHARLQDLLLHY 1JU5 Chain:A ((2-93)) WYWGRLSR----------QEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRI-G-DQEFDSLPALLEFY

General information: TITO was launched using: RESULT: Template: 1JU5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 207 -23766 -114.81 -321.16 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -114.81 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.447

(partial model without unconserved sides chains): PDB file : Tito_1JU5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JU5-query.scw PDB file : Tito_Scwrl_1JU5.pdb: