Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKLEVKDNKKLVLKSVICKKLHDTKV--EDV--------DQEINRFHQHLQLLKAQIFGPLIVKSCGTTIH-DDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVRFEDSPEYLQYAYSKLD-LYVYENDIQTD-GIVYTVYVNSS---PEKMVVDIFIPIVSL 1D5Y Chain:A ((128-287)) --------FVTLEDTPLIGVTQS-YSCSLEQISDFRHEMRYQFWHDFLGNAP----TIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQG-GEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDDRPINLRCELLIPIRR-

General information: TITO was launched using: RESULT: Template: 1D5Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 542 3580 6.60 25.57 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 6.60 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_1D5Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1D5Y-query.scw PDB file : Tito_Scwrl_1D5Y.pdb: