Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVMNLLFFREIEKTKASNFIQLSDWIATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERERVYWRR 1M6N Chain:A ((411-473)) ----------------------------MEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKN-KGIPHQVLNAKNHEREAQIIEE--

General information: TITO was launched using: RESULT: Template: 1M6N.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 128 -23157 -180.91 -367.56 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -180.91 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.663

(partial model without unconserved sides chains): PDB file : Tito_1M6N.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1M6N-query.scw PDB file : Tito_Scwrl_1M6N.pdb: