Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------MSRLLVIGCGGVAQV---AISKICQDSETFTEIMIASRTKSKCDDLKAKLEGKTSTKIETAALDADKVEEVIALIGSYKPEAVLNVALPYQDLTIMDACLATGVHYIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSGFDPGVTSVFSAYALKHYFDEIH-------------------YIDILDCNGGDHGYP--------FATNFNPEINLREVSAPGSYWEDGK-------------------WVEVEAMSI-KREYDFPQVGQKDMYLLHHEEIESLAKNIPGV--KRIRFFMTFGQSYLTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIF-TGVKDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPA-MIGTKLVMNGTWKQAGVYNLEELDPDPFMEALNEYGLPWVVVE--------------------NPQMVD------- 2PH5 Chain:A ((6-474)) NTKKILFKNRFVILGFGCVGQALMPLIFEKFDIKPSQVTIIAAEGTKVD-------VAQQYGVSFKLQQITPQNYLEVIGSTLE-ENDFLIDVSIGISSLALIILCNQKGALYINAATEPWKERRT--------------------NYSLREEVLRLKDKTQKTALITHGANPGLVSHFIKEALLNIAKDNGLTINRPKNAAEWANLAMTLGIKVIHVAEQDSQVTYPPKSPGEFVNTWSANGLILEGLQPAEIGWGTHEAHWPHDAYSHSNGPQCAIYLSRPSAGVMVRSW-TPTLGAFHGFLITHAETISLTNFLTLKNGSELLYRPTVHYAYNPCPDARLSIFELKSNEWKPQNKNRLILNEIID-------------GCDELGVLLMGNQRG----AYWYGSTLSIQEARQIAPYNNATSLQVVASMISGIIWAIEH--PDEGIVEPEEVDHQYIIDIAKPYLGKVGGYYTDWTPLKNRGELYPEEVDLSDPWQFFNIRVNLE

General information: TITO was launched using: RESULT: Template: 2PH5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1919 439 0.23 1.18 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 0.23 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.352

(partial model without unconserved sides chains): PDB file : Tito_2PH5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PH5-query.scw PDB file : Tito_Scwrl_2PH5.pdb: