Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSL----VSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA 4P81 Chain:C ((8-179)) -----VLDEQAIRRALTRIAHEIIERNKGVDNCVLVGIKTRGIYLAKRLAERIEQIEGKKVPVGELDITLY------------KGTDIPVDITDKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNVPTSKSERIVVQLSEVDGQDRVSIYE--

General information: TITO was launched using: RESULT: Template: 4P81.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 797 -39988 -50.17 -259.66 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain C : 0.89 3D Compatibility (PKB) : -50.17 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.89 QMean score : 0.656

(partial model without unconserved sides chains): PDB file : Tito_4P81.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P81-query.scw PDB file : Tito_Scwrl_4P81.pdb: