Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTLAKIEALLFVAGEDGIRVRQLAELLS--LPPTGIQQSLGKLAQKYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQPITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHLEELPVIDELEIQAQESQLFGERIEEDENQ 1T6S Chain:B ((6-162)) QQLLRSLEALIFSSE-EPVNLQTLSQITAHKFTPSELQEAVDELNRDYE-ATGRTFRIHAIAGGYRFLTEPEFADLVRQLLAPVIQRRLSRSMLEVLAVVAWHQPVTKGEIQQIRGASPDYSIDRLLARGLIEVRGRADSPGRPLQYGTTEVFLDLFHL--------------------------------

General information: TITO was launched using: RESULT: Template: 1T6S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 475 5417 11.40 34.95 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : 11.40 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.580

(partial model without unconserved sides chains): PDB file : Tito_1T6S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T6S-query.scw PDB file : Tito_Scwrl_1T6S.pdb: