Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALLRIEKNNGIATVYLNRPDKRNAMSFALLKELVTTAKAIQKDRDIRCVILTGEAQVFSAGIDLSD-----LNNPKNSAFAIWELVKPGQSLFQKAFLIWQNLPVPVIAALEGYCFGAGMQLALAADIRIAHPDTKMSIMESRWGLVPDMGLTRSLKGLIG-VDLAKELTLTARVLDGNYAKDIGLVTHLSENP---LEKANAIASEMLQRSPDALTAAK-RVLDAMEHQPEKSLRLEKIWQLKLLLGKNSKLARKKDKHPEVKFLPRQYR 1DCI Chain:B ((17-249)) --------------VQLNRPEKRNAMNRAFWRELVECFQKISKDSDCRAVVVSGAGKMFTSGIDLMDMASDILQPPGDDVARIAWYLRDLISRYQKTFTVIEKCPKPVIAAIHGGCIGGGVDLISACDIRYCTQDAFFQVKEVDVGLAADVGTLQRLPKVIGNRSLVNELTFTARKMMADEALDSGLVSRVFPDKDVMLNAAFALAADISSKSPVAVQGSKINLIYSRDHSVDESLDYMATWNMSML-------------------------

General information: TITO was launched using: RESULT: Template: 1DCI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1067 -33052 -30.98 -148.22 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -30.98 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_1DCI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DCI-query.scw PDB file : Tito_Scwrl_1DCI.pdb: