Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKPNDVVSNLLNNPTPNTHASVDSAQQEQQAGLDFVRQVITDDLAAGRAKQIVTRFPPEPNGYLHIGHVKAICLNFGVAEEFNGLCNLRFDDTNPDAEEQEYVDGIANDVKWLGFS-WNGEPRYASGYFDQLYAWAIQLIEQGDAYVDLQSPEEIKLNRGSFVE--PGKN---SPYRDASVEENLARFEKMRNGELKEGEAVLRAKIDMASPNVHMRDPILYRVLHSEHHQTGDKWKIYPMYDYAHPLSDAIEGITHSLCTLEFQDHRPFYDWIVEKVKPKAVPHQYESSRLNVDYTITSKRKLRKLVEGGYVNGWDDPRMPTVVGMRRRGFTPEGLRDFCKRVGVSKTDGIVDVAMLEFCIRQSLENTAARGMAVLNPLKVTLTNLPED---LDLTHARHPNVDMGERVIPLTKEIYIDRKDFEE-VPPKGFKRLIPD---GEVRLRHAYVIKCDEVIKDANGEVVELKCSIDPDTLGKNPEGRKVKGVIHWV--SATKGIP---AEVRIYDRLFTEADPETG-DDFLANLNPDSLKVV-QAVIEPALA------------------------QAKPEDRFQFEREGYFVADQYDHTPEKPVFNRVLDLKDSFKPEKK 4H3S Chain:A ((251-806)) --------------------------------------------------KVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPW--KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGI---GTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHV-FRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLE--KDEAGKIIRIHVNYD-NK-------KKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRVGYFTLDK-ESTTSKVILNRIVSLKDA------

General information: TITO was launched using: RESULT: Template: 4H3S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2472 47856 19.36 95.33 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : 19.36 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.460

(partial model without unconserved sides chains): PDB file : Tito_4H3S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H3S-query.scw PDB file : Tito_Scwrl_4H3S.pdb: