Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNFIKKWSVGLLSMLPVLAMAHPGHDHVHSGFMAGFIHPFTGLDHLIMALGFGVLLWS---AAKQWKIA---GVITLSITL----VIGFLV--GAQGLVPANV--AEYGIVTSLIITAIALWTKSNRILPIAAALLASFHGMAHGVELAHAGHIVALVTGMVAGMALIYCGGLALGAVFTRYVPYGKKIVGACAALVAVIGLS 1JXP Chain:A ((3-179)) ---ITAYSQQTRGLLGCIITSLTGRDKNQV---EGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCT------RGVAKAVDFVPVESMETTM--------------

General information: TITO was launched using: RESULT: Template: 1JXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 775 -69290 -89.41 -425.09 target 2D structure prediction score : 0.18 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -89.41 2D Compatibility (Sec. Struct. Predict.) : 0.18 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.006

(partial model without unconserved sides chains): PDB file : Tito_1JXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JXP-query.scw PDB file : Tito_Scwrl_1JXP.pdb: