Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRPTVLCFSGLDPSGGAGLQADIEAIGQSGAHAAIACTALTIQNSQQVFGSEATSKELLLAQANAVVGDLPIKCVKSGMLGTTDNIAALAEFLRAHPDYQYVLDPVLVANSGGSLGDQATLVKAFVELILLATLITPNTVELRALTGV----TDLDQATQ--KLFEMGAKAVLVKGGHEDTPDFIKNSLYIDGELAASSTCPRLEGE-YHGSGCSLASFIAGRLALGDSLKIAVQHAETWLFGVLKNAETPVPNGQKIPKRF 1JXI Chain:B ((25-271)) -RINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAENTCGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRHHVRNVVLDTVMLAKSGDPLLSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLAQGRALLAMGCEAVLMKG------DWL---FTREGEQRF-----RVNTKNTHGTGCTLSAALAALRPRHRSWGETVNEAKAWLSAALAQADT------------

General information: TITO was launched using: RESULT: Template: 1JXI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1283 -89753 -69.96 -393.65 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -69.96 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.501

(partial model without unconserved sides chains): PDB file : Tito_1JXI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JXI-query.scw PDB file : Tito_Scwrl_1JXI.pdb: