Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAVNFNMRLEAELKEQVTPILEDY-GLTMPQAFKLFLNQIVKTKAIPLSFDYARETALTPKAAAKLLQSLKEIENGEYTEYETVEEAIKAMSEEAHG 4Q2U Chain:A ((3-86)) -ANAFVRARIDEDLKNQAADVLA-GMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQSIKNSEAGIDVHK--------AKDADDLFDKLGI----

General information: TITO was launched using: RESULT: Template: 4Q2U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 95 -3947 -41.55 -47.55 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -41.55 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.444

(partial model without unconserved sides chains): PDB file : Tito_4Q2U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Q2U-query.scw PDB file : Tito_Scwrl_4Q2U.pdb: