Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQTQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDE--------KDAIEIQRLYLLKDYQNKGLGQRLLDEANRYAKTNKNVIYV 1TIQ Chain:B ((2-127)) ---SVKMKKCSREDLQTLQQLSIETFND--------ENMKAYLESAFNTEQLEKELSNMSSQFFFIYFDHEIAGYVKVNIDDAQSEEMGAESLEIERIYIKNSFQKHGLGKHLLNKAIEIALERNKKNI-

General information: TITO was launched using: RESULT: Template: 1TIQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 410 -21574 -52.62 -196.13 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -52.62 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.380

(partial model without unconserved sides chains): PDB file : Tito_1TIQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TIQ-query.scw PDB file : Tito_Scwrl_1TIQ.pdb: