Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLPKALKTKDRILQISLQLFNERGERSVTTNHIAAELGISPGNLYYHFRNKHEIIKELMHQYQVETLEMLSLPED--RPLTTNDKINYFQVLSGQLWNYRFIHRDVYHLV-ESNEDFKKIYPRFAGQVMQQGQRIYQAFVDAGLMKMTPSEIEALIINLWIVLTNWTNFLYMSRHISDNNHLEEKWVWQALRQMVFLEGPYLMGESRATYEQLLESLGPSDLFASLSSLKDE 3KZ9 Chain:B ((12-201)) --RLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDEVLNHVVRQFSNFLSDNIDLDLH-AKENIANITNAMIELVVQDNHWLKVWFEWSASTRDEVWPLFVTTNRTNQLLVQNMFIKAIERGEVCDQHN-PEDLANLFHGICYSLFVQANRT--------NNTAELSKLVSSYLDMLCIY-------------------------------

General information: TITO was launched using: RESULT: Template: 3KZ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 695 -53698 -77.26 -287.16 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.63 3D Compatibility (PKB) : -77.26 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.393

(partial model without unconserved sides chains): PDB file : Tito_3KZ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KZ9-query.scw PDB file : Tito_Scwrl_3KZ9.pdb: