Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAYTASCLCNGIQLRINAE--LEPIMVCHCKQCQKAQGAAFAAITQVQKSDLEIVQGENLLQAYFA-SPNKKRVFCKICGSPVWSERLDKPDVVRLRVGLINEEISTPVISHAFVNSQVKWYPICDTARQYPNGVENP 3FAC Chain:F ((1-109)) --MKGTCHCGAVEIEVELLNGFADARRCDCSFCRRRGAIA----ATARLSDLRVVRGAENLTLYQFGTRTAKHWFCRTCGIYTHHQRRSNPEEYGVNVAILEGVNPRDLGEVPWT-----------------------

General information: TITO was launched using: RESULT: Template: 3FAC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 496 -25844 -52.10 -243.81 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain F : 0.67 3D Compatibility (PKB) : -52.10 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.369

(partial model without unconserved sides chains): PDB file : Tito_3FAC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FAC-query.scw PDB file : Tito_Scwrl_3FAC.pdb: