Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNALTQELVELLTLEKLEENIYRGISRN-LVG-----KRVFGGQVLGQALRAASYTTDRPAHSLHAYFLYGGDINAPIIYEVDRLRDGKSFVSRQVRAIQHGRVIFSAMVSFANPEEGLNYQ-HPEPDYPAPEALKSESELKEGILNFVPENVRASFMRERHVEIRPIDPVNPFQPQPEAPFNAHYIRTHDRIPKQLEDISLHQAIVAFYSDFTLMTTALRPHGLSYISPSL-QCASIDHAIYFHRPLRADEWMLYDMEATVSAASRGLNFGRMW-QNGQLVCSTVQEGLMRLREIETQ 3CJY Chain:A ((5-258)) ---------AFPALVRQDDARYAITVGPDLAVGPPGHAYLFGGASMALALDVAAETVGRPVVQGSLQFVSFTPLGSVLDLTVEVLQSGRTLAQARVAGTVDGRLVFHSGISLGMREGFSARQWALAPPVPQPDNCPPCTTLPAQD---D---NA-RY--LEGIEVREAGGP-----EVPSGRTRLWLRRKD-------GAPLDAASLAMFADFLPIALG-RAT------GCSG--NSLDNSLRITG-AAAPGWCLCDMIIPSSASGFAQGQVTLWDQSGRLLATGAQSLLLK-------

General information: TITO was launched using: RESULT: Template: 3CJY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1343 -18713 -13.93 -77.01 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -13.93 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.323

(partial model without unconserved sides chains): PDB file : Tito_3CJY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CJY-query.scw PDB file : Tito_Scwrl_3CJY.pdb: