Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMNSSTEQIISNSLSLRLKQETAAEHERMHQLMSE---AKVFSSKEKYAQFTLSQYYFQLEIEHLFEKEGVAGLI--PDLDIRGRSKQALADLNDLGIQPNG------QQ----------LQSENVQLPEALGWIYVS-EGSTLGAAFLFKEAQKHLGFSETFAARNLAAYPEGR-AKVWKRFVKALDEAGFDQTQQDRVVQGALDAFGYFGQALDQLDELK 1WZD Chain:A ((7-213)) ------------GLAVELKQSTAQAHEKAEHSTFMSDLLKGRLGVAEFTRLQEQAWLFYTALEQAVDAVRASGFAESLLDPALNRAEVLARDLDKLNGSSEWRSRITASPAVIDYVNRLEEIRDNVDGPALVAHHYVRYLGDLSGGQVIARMMQRHYGVD-PEALGFYHFEGIAKLKVYKDEYREKLNNLELSDEQREHLLKEATDAFVFNHQVFADLGK--

General information: TITO was launched using: RESULT: Template: 1WZD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 694 22171 31.95 120.49 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 31.95 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_1WZD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WZD-query.scw PDB file : Tito_Scwrl_1WZD.pdb: