Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRQLQLDIEPQLDARISDFSGPG-WGHVVDAVRQLHAGL--VNRFYIYGGAGTGKSHLLSAICDSYLEV--GKSAIKVSLLELLDA---------PIEAITCLE-HYDLVALDDIESISGVPHWQKAVFHLMN---NHEGQLVFSSRVAPIELKLELPDLQSRLTQAVSVKVPSGSLYADRYALVTSVMARRGIHFDQQIVDYLLLHGPHQASVLLQTVAQLEKLLKGEKTKLSNATLRQIYALIDEYQQ 2Z4R Chain:C ((98-332)) ---------LNPDYTFENFVVGPGNSFAYHAALEVAKHPGRYNPLFIYGGVGLGKTHLLQSIGNYVVQNEPDLRVMYITSEKFLNDLVDSMKEGKLNEFREKYRKKVDILLIDDVQFLIGKTGVQTELFHTFNELHDSGKQIVICSDREPQKLSEFQDRLVSRFQMGLVAKLEPPD-EETRKSIARKMLEIEHGELPEEVLNFVAENVDDNLRRLRGAIIKLLVYKETTGKEVDLKEAILLLKDF-----

General information: TITO was launched using: RESULT: Template: 2Z4R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1038 3747 3.61 17.26 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain C : 0.69 3D Compatibility (PKB) : 3.61 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_2Z4R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Z4R-query.scw PDB file : Tito_Scwrl_2Z4R.pdb: