Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWCFKNGQPVETIPLLDRAFHYGDGCFTTIRVFQNKIELKARHWERLKLACQKLSLV-ADFELIEQSLQRLQNQNLVLNGTLKIVISRGEGDRGYSLPKHA--ADI--YI-WFYPKALEQFQPDFIQCGVLNQALGLTMPSLVGLKSLNRLEQVLLKKEADQQGWVEALVTDVQGYIVEGVSSNCFIRLNDRWITPELRYNGVHGVMRAEILVRMQHYGIACEVRIIELDEVPQIQSLFFCNALHPMRVVTQISEQILESQACLNLFHTLNLNQIH 1I2L Chain:A ((1-267)) -MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQRLQDACQRLMISCDFWPQLEQEMKTLAAEQ--QNGVLKVVISRGSGGRGYSTLNSGPATRILSVTAYPAHY--DRLRNEGITLALSPVRLG-RNPHLAGIKHLNRLEQVLIRSHLEQTNADEALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVEVQASLEESLQADEMVICNALMPVMPVCACGDVSFSSATLYEYLAPLCER---

General information: TITO was launched using: RESULT: Template: 1I2L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1418 -47116 -33.23 -180.52 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -33.23 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.402

(partial model without unconserved sides chains): PDB file : Tito_1I2L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I2L-query.scw PDB file : Tito_Scwrl_1I2L.pdb: