Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAEFIAVILITILAVISPGADFAIVTKNSYLYGRKIGVFT--SLGISLGVLVH--------VTYTLVAVAFVMTYTPQILNIVKYIGALYLIYIGYKTFTQKPVLETTALTAIGTFQAIKYGFFTNALNPKTTLFVISTYTQIVSLTTPKSILLAYGFFMSFAHFVWFSLVAVLFSSMLLRQKMLAKQVQINRVIGSILCVLGVILLFTKFQ 1QP2 Chain:A ((1-77)) --------------MVQRGSKVRILRPESYWFQDVGTVASVDQSGIKYPVIVRFEKVNYSGINTNNFAEDELVEVEAPKAKPKK--------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1QP2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 225 -25052 -111.34 -417.53 target 2D structure prediction score : 0.25 Monomeric hydrophicity matching model chain A : 0.45 3D Compatibility (PKB) : -111.34 2D Compatibility (Sec. Struct. Predict.) : 0.25 1D Compatibility (Hydrophobicity) : 0.45 QMean score : 0.218

(partial model without unconserved sides chains): PDB file : Tito_1QP2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QP2-query.scw PDB file : Tito_Scwrl_1QP2.pdb: