Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WTGKSEASNRPPPGRRPEETTWFTSD--PSYACGVKIFRPGSEGS--SGLAEI---THLNFHEKIKVLKGQYECEVGPSCS-TLRCTMPRGWRLDIFGKSFPTRRTTYFAENGNPEYNTLASEANIPLYDCRVVIRFPPTGGRDT--GPLAEATHFNLGEVVGVLGGRHTCQAQGQCANVNCNVPKGYTYYSLTGG-------PFQTKEKSHTFQSDA---------------- 1QRE Chain:A ((38-247)) -TVDEFSNIRENP-----VTPWNPEPSAPVIDPTAYI----DPQASVIGEVTIGANVMVSPMASIRSDEGM-PIFVGDRSNVQDGVVLHALETINEEGEPIE---DNIVEVDGKEYAVYIGNNVSL---AHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNC-VLEPR--SAAIGVTIPDGRYIPAG----MVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLAEGYKETS

General information: TITO was launched using: RESULT: Template: 1QRE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1074 37592 35.00 212.38 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 35.00 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.282

(partial model without unconserved sides chains): PDB file : Tito_1QRE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QRE-query.scw PDB file : Tito_Scwrl_1QRE.pdb: