Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSISMLKKYPCTMQHDQSDCAAAVVSTVLLSYKKEL------------SIMKIREI---------IGTDMYGTTVSGIVSGLNKLNFTVKAVRVALED 2BTW Chain:A ((68-155)) ------LSMQFVTQVNQAYCGVASIIMVLNSLGINAPETAQYSPYRVFTQDNFFSNEKTKAVIAPEVVARQGMTLDELGRLIASYGVKVKVNHA----

General information: TITO was launched using: RESULT: Template: 2BTW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 206 -5610 -27.23 -83.72 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -27.23 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.410

(partial model without unconserved sides chains): PDB file : Tito_2BTW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2BTW-query.scw PDB file : Tito_Scwrl_2BTW.pdb: