Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------------------------------------------------------------------------MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTMMAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI 1U8S Chain:A ((2-180)) SLTQHLVITAVGTDRPGICNEVVRLVTQAGCNIIDSRIAMFGKEFTLLMLISGSPSNITRVETTLPLLGQQHDLITMMKRTSPHDHQTHAYTVEVYVESDDKLGLTEKFTQFFAQRQIGMASLSAQTISNQFHIAISARVDSGCNLMQLQEEFDALCTALDVQGSLNFIKN-------

General information: TITO was launched using: RESULT: Template: 1U8S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 342 17993 52.61 222.13 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : 52.61 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_1U8S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1U8S-query.scw PDB file : Tito_Scwrl_1U8S.pdb: