Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKEMLEAFRILEEDKRIKKEDIIDAVVESLRSAYRRRYGQSDSVAIDFNEKTGDF-TVYTVREVVDEAFDSRLEISLKDALAINSAYELGDKIKFEEAPAEFGRVAAQSAKQTI-MEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQLSKQDQ-IPGEVFASHDRIEVYVYKVED-NPRGVNVFVSRSHPEMIKRLMEQEIPEVYDGTVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDRMVPIEENIDVIEWVADPAEFIYNAI-APAEVDQVIFDE-SDSKRALVVVPDNKLSLAIGRRGQNVRLAAHLTGYRIDI-KSASEFEAMEDAASVELEVENDTVEE------------------------------------------------------------------- 4MTN Chain:A ((5-406)) -GNEVLRIVDSIHRDKSIDKEIVFEGVEQAILSAARKHFGEEEVIEVHIDRTSGQPMVKTNGRE-----------------------------IDRDELGDILGRISAQTKQ--VMIQKIREAERDTLFDEYAQLRGQIVSGTVTRNEGSAITVNIGKAEAILPR-SEMIPGESHRPNERIRAVVLEVKKMGPR-VRVVLSRAHPDFVRRLLELEIPEVNERIIEIRSLAREAGYRTKVAVSCADSNIDPVGACVGVRGARIRNVGEELG--------------GERIEVVRWNDSLQVLVPNA-MQPSEVEDVILCPMLG--RVLVLVRDDQLSLAIGKRGQNVRLASKLVGWDIDVMTREELDQQLDQAVVAYSQIPGVSEELAEGLVSQGFLSFEDLSVIEPDELMEMGSLTQEQADVIVEYAERESERIEKEQDLRRATEKAERQSQE

General information: TITO was launched using: RESULT: Template: 4MTN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1438 42190 29.34 129.02 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 29.34 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.466

(partial model without unconserved sides chains): PDB file : Tito_4MTN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MTN-query.scw PDB file : Tito_Scwrl_4MTN.pdb: