Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFLSQIDEMLIGDLDLQFVMPWEFEDLNPEAFREFNRELYAHRFDLDYESYSVDNDIDLHLSNYYSSCETNKLIP-SNCFFKLVEYMLVVLESRS-FTSLFSNCVEFYNTKYSNEYLTFFLNLFSTSKSEVARDNLRMYITEIFDDKR---YWANNELFDDSLLFEENLQQLQIIRVM 1Y9L Chain:A ((6-115)) -------------------------------------------------------------------EKEWHIVPVSKDYFSIPNDLLWSFNTTNKSINVYSKCISGK-AVYSFNAGKFMGNFNVKEVDGCFMDAQKIAIDKLFSMLKDGVVLKGNKINDTILIEKDGEVKLKLIRGI

General information: TITO was launched using: RESULT: Template: 1Y9L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 422 8804 20.86 83.85 target 2D structure prediction score : 0.29 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 20.86 2D Compatibility (Sec. Struct. Predict.) : 0.29 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.173

(partial model without unconserved sides chains): PDB file : Tito_1Y9L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y9L-query.scw PDB file : Tito_Scwrl_1Y9L.pdb: