Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDLPQNDEYDRRFAGVAKIYGDSSFQHYEQSHVMVIGIGGVGSWAVEALARTGIGEITLVDMDVVAASNVNRQLPAMTSTLGCEKVEIMAERCRQINPRIKVNIIDDFLTPENVAELLNPVPDIVLDCIDDVKAKLALMLHCRFNKIPLIVSGGAGGKLDPLKIRVADLSKTEQDPMLAKLRSQLRAR-GICKKPKEKFGITCIYSIDN---PFSSADVCPSAGLRCGGYGSAVVVTSSFAMIAVAEVLKKLDLKKA 4D79 Chain:B ((6-265)) ------SDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSD------------GFGAATMVTATFGFVAVSHALKKMMAKAA

General information: TITO was launched using: RESULT: Template: 4D79.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1345 -165099 -122.75 -699.57 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.84 3D Compatibility (PKB) : -122.75 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.599

(partial model without unconserved sides chains): PDB file : Tito_4D79.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4D79-query.scw PDB file : Tito_Scwrl_4D79.pdb: