Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSYSASYLPRMQQNLTLLQHYHENKENCMSFSMTKLSAALLLTSSLVGCAAVVKTPYQAPAVQVPGSFQYDKAKAKTASVEQ---YSDHWWTLFGDAQLNQLVTNVLERNSDLAVAGITLKQARLQADLTANKQGLRTSSSVS------TGHSFDLNSGDDSAKGLSMSAGVSYELDLFGKLARQTEASKWEALATEQDLQSTGQSLIATTAKLYWQLGYLNERYATAQQSLATSQKLYQLVQTQYKAGAVSGLDLTQAEQSVQSQKASLSQIEQQLVETRTAIAVLLHEPVQQLNIQEPQRLPRTALPAIGAGLPADILSRRPDLQAAELRLRKALATKDATKASYYPSISLTSSLGSSSTSLTELLRNPAL--TLGASLSLPFLQYNDIKKDIAISNLDYEKAIIQYRQTLYQAFADVENALSSRTELDKQVALQERNVELAEKTERLTEVRYRYGAVALKTLLDAQQTTRTARLSLVETKQSQYNAYVTLMQALGGSPVKELPQ 1WP1 Chain:A ((1-456)) ---------------------------------------------------CSLIPDYQRPEAPVAAAYPQGQAYGQNTGAAAVPAADIGWREFFRDPQLQQLIGVALENNRDLRVAALNVEAFRAQYRIQRADLFPRIGVDGSGTRQRLPGDLSTTGSPAISSQYGVTLGTTAWELDLFGRLRSLRDQALEQYLATEQAQRSAQTTLVASVATAYLTLKADQAQLQLTKDTLGTYQKSFDLTQRSYDVGVASALDLRQAQTAVEGARATLAQYTRLVAQDQNALVLLLGSGIPANL-PQGLGLDQTLLTEVPAGLPSDLLQRRPDILEAEHQLMAANASIGAARAAFFPSISLTANAGTMSRQLSGLFDAGSGSWLFQPSINLPIFTAGSLRASLDYAKIQKDINVAQYEKAIQTAFQEVADGLAARGTFTEQLQAQRDLVKASDEYYQLADKRYRTGVDNYLTLLDAQRSLFTAQQQLITDRLNQLTSEVNLYKALGGGWNQQTVT

General information: TITO was launched using: RESULT: Template: 1WP1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1717 54495 31.74 122.46 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 31.74 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.353

(partial model without unconserved sides chains): PDB file : Tito_1WP1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WP1-query.scw PDB file : Tito_Scwrl_1WP1.pdb: