Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MTELTPYHEDQELDNNTSDNIHFRDILEQHISRRSLITKAASGAVALTLASTLTGCNDNDDDSGSNNGGTTPVDPNKKPEKLTFTPVAKNLNDIVTVPEGYEANVIYALGDSINPRVGDWDDNNIPSGPSFQFRSGDCHDGMHYFGLNTSTNRFDETVSAQGLLVMNHEYINQTFLHPKGPTKVDGRRPEDEVIRETNANGVSVI--------HIKKDPTTQKVEIIKNSIFNRRITASTVMEFAGAAAGS----------SLLATRFSPAGRQTRGTHNNCGNGYTPWGTYLTTEENFIGYFQRSGSDEYARTDAEKITLKRYGLGVKKDEPYLYEKDE-----KGAPKKDKD---GKIIYLKDKNGELIPNVDEQGRQIYLGTSSRYGWETAIGQVESQDLYDRWNADVKAAQATQDYRNGPNTFGWMVEIDPFDGRQNPVKRTSLGRFAHEDSACRAV-VGQPLAFYMGDDSRGEYIYKFVSTAVWDTKDINGGYTAGDKYMNAGKLYVAKFNNDGSGQWIELAYGKNGLNESNTTYPFKSQADVVTFARLAADSVG--------ATKMDRPEWCTINPLNGEIYVTLTNNSNRG--------KDYATDAANPRNYTDLYAGTKEQKGNVNGHIIRFKETDDKTTAETFKWDIYLFGAEAAMASNINLSGLTDNNDFSSPDGMWFDPRG----VLWIETDDGAYTDVTNCM--MLAALPGQIGDGGTATTSNGQQTITGAKVTDATLRRFLVGPKQCEITGIAMTPDYKAIFINVQHPGEDSPSYAKPESNWPATQKDPSNKTARPRSATVVITRKDGGVIAG 3V97 Chain:A ((1-703)) AMNSLFASTAR-----------GLEELLKTELENL--------GAVECQVVQ---------------GGVHFKGDTRLVYQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAIN-----WTEMFNPGAT----------FAVHFSGLNDTIRN-----SQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLHLRGYRDRAGIAPIK------ETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGLHRG------RWG--------FSGWAQH---DEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNARLAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYG----------ESEPALIALHSLLGRIMKNQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESMV---AEDYTNRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYAD-----WVVVQE-----------YAHKARQRLFDIIAATISVLGIAPNKLVLKTREEKGEFLEVTEYNAHLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYT----GSATVHAGL---GGARSTTTVDMSRTYLEWAERNLRLN-GLTG-RAHRLIQADCLAWLREANEQFDLIFIDPPTFSAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKR---GFRMDLDGLAKL--GLKAQEITQKTLSQDFA---------------------------------RNRQIHNCWLITAA-------

General information: TITO was launched using: RESULT: Template: 3V97.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3386 116129 34.30 188.22 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 34.30 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.202

(partial model without unconserved sides chains): PDB file : Tito_3V97.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V97-query.scw PDB file : Tito_Scwrl_3V97.pdb: