Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMNKQPQNSALVVVDVQNGF-TPGGNLAVADADTIIPTINQLAG--CFENVVLTQDWHPDNHISFAANHPGKQPFETIELDYGSQVLWPKHCIQGTHDAEFHPDLNIPTAQLIIRKGFHAHIDSYSAFMEADHTTMTGLTGYLKERGIDTVYVVGIATDFCVAWTALDAVKQGFKTLVIEDACKGIDLNGSLEQAWQT----MQQQGVIRIQSTDLLNEC 3R2J Chain:C ((37-223)) -----------LIIADMQVDFLAPGGSLHVKGGEALLDGINAVSSQLPFRYQVATQDWHPENHCSFV-THGGP---------------WPPHCVQGSAGAQLHAGLHTQRINAVIRKGVTQQADSYSAFVE-DNGVSTGLAGLLHSIGARRVFVCGVAYDFCVFFTAMDARKNGFSVVLLEDLTAAVD-----DAAWSARTAELKDAGVVLLKSSALVAE-

General information: TITO was launched using: RESULT: Template: 3R2J.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 988 -17386 -17.60 -96.59 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -17.60 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_3R2J.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3R2J-query.scw PDB file : Tito_Scwrl_3R2J.pdb: