Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIEELLPFYEKQLQEFGQQSREFAQKYPKIAQR----LSLNQEQI-DDPHIERLIQAFSLIAARIDKKLTDSYDVFTRSLFEVMFPQYLRHF--PACSVVSFEDINKIKQLTEPHLVP-HHTVLKSRSFKGVQCEFNTTQDVRLLPIHLSGLDFKTTPSAHMHLNQN-ATLSLKF--EIFNNAHACLTDEKLPIYLDAI-SNFPLQVLDSIFKKGTSFAVKYGQIIVELSKNPFELTGFAEQESLLP--LDQHTHHAYRLLMEYFCFPEKFSYLKLDLDFLKRIPQHVSEFELLIHFKLNLNDQAVVRNYSELNIAN----FKLFTTPVINLF-----------------------EKYAEPQKIVHKQLEYPLVTDAHH--------PEFYQVYSILEMNMVREKTNQEESYVPVLPFFAMSHYHNDTARFFYSVNY----QKLQSNFVEMGYSII-SKNLNPFSTRSDFISTKLLCSNRDLPHEALGQSNNVLNLNDSSLARRAIV---LKRPTKPYKFEQGQSEQWRVISHLSLNSLALMKGDAVSLVKELLALYNLPQSKENYLIIESIKKLEFSLTHKLVDGKPFPMFVRGVKAELQIDSSVFRGHS---LYIFSQLLSRVFNLKVQINSFVDLVVKDYSSQQELYQCSQNVGGKTLL 4X0Q Chain:A ((6-772)) ---------SLSIIDVASDQNLFQTFIKEWRCKKRFSISLACEKIRDDTLVVGLAVCWGGRDAYYFSLLDPS---LTLKDRMWYLQSCLRKESDKECSVVIYDFIQSYKILLLSCGISLEQSYEDPKVACWLLD--PDSQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRYRASVESILIFNSMNQLNSLLQKENLQDVFRK-VEMPSQYCLALLELNGIGFSTAECESQKHIMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLPPQFSTSKDVLNKLKALHPLPGLILEWRRITNAITKVVFPLQREKCLNPFLGMERIYPVSQSHTATGRITFTEPNIQNVPRDFEIKMGMPFSISMRHAFVPFPGGSILAADYSQLELRILAHLSHDRRLIQVLNTG---ADVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSR-YTGINQFMTETVKNCKRDGFVQTILGRRRYLPGIKDNNPYRKAHAERQAIN--TIVQGSAADIVK--IATVNIQKQLETF------HSTFKSHGHREGMLQS-DCPIRGGFFILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKLSVKLKVKVKIGASWGELKDFDV--------

General information: TITO was launched using: RESULT: Template: 4X0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2494 38052 15.26 67.35 target 2D structure prediction score : 0.33 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 15.26 2D Compatibility (Sec. Struct. Predict.) : 0.33 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.173

(partial model without unconserved sides chains): PDB file : Tito_4X0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4X0Q-query.scw PDB file : Tito_Scwrl_4X0Q.pdb: