Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLNLMLGFASGVMIA----ASFWSLLDPAITKAEENGDIAWL---VVSIGFGLGGVFLYMADKTLPHMHFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVSVALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELLLPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG 5IMU Chain:A ((4-220)) -AGAVSARAAEQQRLQRIVDAVARQEPRISWAAGLRDDGTTTL-LVTDLAGGWIPPHVRLPANVTLLEP--TARRRDADVIDLLGAVVAVAAHESNTYVAEPGPDAPALT-GDRSARSAIPKVDEFGPTLVEAVRRRDSLPRIAQAIALPAVR----------------------------------KTGVLENEAELLHGCITAVKESVLKAYP-----------SHELTAVGDWMLLAAIEALIDE--QDYLANYHLAWYAVTTR----------RG

General information: TITO was launched using: RESULT: Template: 5IMU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 930 -71022 -76.37 -338.20 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -76.37 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.226

(partial model without unconserved sides chains): PDB file : Tito_5IMU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IMU-query.scw PDB file : Tito_Scwrl_5IMU.pdb: