Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKMTRRSTMLETYLEKSIFRQVYICEQLHEK-GTIQIREIADQLNVCPLTVTNDLECITDILHQQIISVEKSRSSFTVAFDSSFSRLALTQLIYQRSDFFNVLGHYLSGEH-NWSNIADTTFISLSKVYNLRNELINFFK-QMQYLNAD--GHFEIPEKDYRSLLLT-IIYETNRTELIQLNKSIIQSGQQLIDYVEKHFFSRSYPTVEKQFILLGIAIGLQRSKTNPIYFSQEEKRVAR---HTPLFQLIQKGLEQLSFSLCHDEDECLYIYFLFNSRNYLCDNFELLQKDLNVVYQNHVADNPLVIELSQKLILSLNISEENQILFDKALLPFIRSLWADIQIFQ--------PDKTYLLNEEQRALYLEVHEILEQWRKQNNLFLR--WNENSIRKLTISLSLLN-E-HKRKSPIEVFIVAPSDFRY-LYYRQQLEDILGEHFSISNIICKQLREIVDDTFFCTQRIILCDSSLYQEGLGSEKTIIYPITFQTIHTVIDQLNKQI 5WAY Chain:A ((1-487)) ----------MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDL--IFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSS-EPLSQLLELVYKET-SFPMNLSTHRMLKLLLVTNLYRIKFGHFMEV--------FLMQAEGIEGVAQSFESE-YNISLDEEVVCQLFVSYFQKMFFIDESLFMKCV--KKDSYVEKSYHLLSDFIDQISVKYQIEIENKDNLIWHLHN--TAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELS--KESLEDSPYDIIISNFIIPPIE----NKRLIYSNNINTVSLIYLLNAMM

General information: TITO was launched using: RESULT: Template: 5WAY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1849 -18850 -10.19 -41.52 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -10.19 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.366

(partial model without unconserved sides chains): PDB file : Tito_5WAY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5WAY-query.scw PDB file : Tito_Scwrl_5WAY.pdb: