Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQMNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGFNLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEK-KVVLA----GGKKLDFDRLILATGSNQKFRNISA---ESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLASRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIV-ETEKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVTFRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEEESIFYPQKIETGYVDYKLTAIN-QSKVKLKFLFDSE-KKILGAQLQSKKEMFHLLDQLTIAVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED 3OC4 Chain:B ((2-426)) -SLKIVIIGASFAGISAAIASRKKYPQAEISLIDKQATVGYLSG---------------ARYITEEELR-RQKIQLLLNREVVAMDVENQLIAWTRKEEQQWYSYDKLILATGASQFSTQIRGSQTEK--LLKYKF------AVPLLENSQTVAVIGAGPIGMEAIDFLVKMKKTVHVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEETANGIVLETSEQEISCDSGIFALNLHPQLAYLDKKIQRNLDQTIAVDAYLQTSVPNVFAIGDCISVMNEPVAETFYAPLVNNAVRTGLVVANNLEEKTHRFIGSLRTMGTKVGDYYLASTGLTETEGLFFPQTLASIIVRQPAPP--HGTEILGKLIYDKVTQRVLGAQLCSKNNCLEKINTLALSIQTGQTLTDLLQKDYFYQPSLTN---------------

General information: TITO was launched using: RESULT: Template: 3OC4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2270 -9337 -4.11 -23.88 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -4.11 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.460

(partial model without unconserved sides chains): PDB file : Tito_3OC4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OC4-query.scw PDB file : Tito_Scwrl_3OC4.pdb: