Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFIELKQG--------TILHRFKHFFGITE-------------- 1E2A Chain:A ((1-102)) MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVVEAGSCIAEAHSSQTGMLAREASGEELPYSVTMMHGQDHLMTTILLKDVIHHLIELYKR

General information: TITO was launched using: RESULT: Template: 1E2A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 122 12948 106.13 205.52 target 2D structure prediction score : 0.86 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 106.13 2D Compatibility (Sec. Struct. Predict.) : 0.86 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.627

(partial model without unconserved sides chains): PDB file : Tito_1E2A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E2A-query.scw PDB file : Tito_Scwrl_1E2A.pdb: