Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL-VKAQGRIQNLKNKINIDTT-GNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVIENFEELKIAYLANDH-FIGETDTEIIAHLIET-FAKDTTTQEAFLKALRVIKGSYAFALIDRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKVIIQNFAGDIVERSSFEA--QVDASDIEKGTYPFYMLKEIDEQPIIMR-----RIAQKYVTEDNRVSLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLLSKKPFFIFLSQSGETADSRQVLVKINRLGY-PSLTITNVAGSTLSREASFTLLLHAGPEIAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYLEELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIEEGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSE--GLEKESDQLV--LPTVHPYLTTLTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE 1JXA Chain:C ((1-608)) -CGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSE--HIVVVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQYDAGD--KGIYRHYMQKEIYEQPNAIKNTLTGRISHGQV---DLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGVASTKAFTTQLTVLLMLVAKLSKLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDF-SDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE

General information: TITO was launched using: RESULT: Template: 1JXA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 3697 14229 3.85 24.03 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain C : 0.83 3D Compatibility (PKB) : 3.85 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.416

(partial model without unconserved sides chains): PDB file : Tito_1JXA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JXA-query.scw PDB file : Tito_Scwrl_1JXA.pdb: