Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLKAIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHRDEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAVRAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWG------LTSEDIASAVAFAIETPDRMSVSNMIIRPTTQEV 3P19 Chain:D ((16-252)) -----KKLVVITGASSGIGEAIARRFSEEGHPLLLLARRVERLKAL--NLPNT--LCAQVDVTDKYTFDTAITRAEKIYGPADAIVNNAGMMLLGQIDTQEANEWQRMFDVNVLGLLNGMQAVLAPMKARNCGTIINISSIAGKKTFPDHAAYCGTKFAVHAISENVREEVAASNVRVMTIAPSAVKTELLSHTTSQ----QIKDGYDAWRVDMGGVLAADDVARAVLFAYQQPQNVCIREIALAPTKQQ-

General information: TITO was launched using: RESULT: Template: 3P19.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1264 -107180 -84.79 -463.98 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain D : 0.81 3D Compatibility (PKB) : -84.79 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.548

(partial model without unconserved sides chains): PDB file : Tito_3P19.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P19-query.scw PDB file : Tito_Scwrl_3P19.pdb: