Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNEKKAVMITKKAGEDMLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVFHPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEETGYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQQAMKDQLICDAKTIYAIQYWELLTKGK 5C7T Chain:B ((3-166)) ----------------------HLEEKTLSTRQIFKGRYLKIEQDQVQAPDGRTYTREYILHPGAAMMIPLLPNGNVVMIHQYRHAVKKVFLEFPAGKRDHNE--ETLLTAKRELLEETGYEAKDWKFLTTIHPVIGYSNEHIDLYLARDLTHLEQRL--DQGQFIEVVEVKPADLMQLVLEGKVSDVKT--------------

General information: TITO was launched using: RESULT: Template: 5C7T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 669 -36989 -55.29 -225.54 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -55.29 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.374

(partial model without unconserved sides chains): PDB file : Tito_5C7T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C7T-query.scw PDB file : Tito_Scwrl_5C7T.pdb: