Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYYFPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLK-MKVERFTDLP 3FGV Chain:B ((13-105)) MREVVIVKSTPQRGKFNAFAELVGK--LVSETRDFPGCLGAYLMLAPER-NEQVVMHIWETPDALEAYLTWRADRGDFLEINEYLEVEQDFKTYQL--

General information: TITO was launched using: RESULT: Template: 3FGV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 356 -26687 -74.96 -290.08 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.62 3D Compatibility (PKB) : -74.96 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.474

(partial model without unconserved sides chains): PDB file : Tito_3FGV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FGV-query.scw PDB file : Tito_Scwrl_3FGV.pdb: