Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence EFHGMISREAADQLLI-VAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYD-GKHFVG-EKRFESIHDLVTD 1K9A Chain:A ((83-161)) -FHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEH

General information: TITO was launched using: RESULT: Template: 1K9A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 243 -19868 -81.76 -283.83 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -81.76 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.619

(partial model without unconserved sides chains): PDB file : Tito_1K9A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1K9A-query.scw PDB file : Tito_Scwrl_1K9A.pdb: