Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGHPPPWTASPLFFLLLFWHAPPSLVSSCLHAGHALHVHPAHNPSLPPLSLPSDRPGAAGDGQTGASLVHNARAALPLCASRVFAGGALQPSTAVPPRTQPLHRCARRYAPSGRLLLKPRLGLKALPIHEVAEGRAEQEDRARPPDPSVSGRTLTCVTLRTKETCNDADCGGLACRTGNATIAGRGARASDGRQPPTKQEGVFPVATSFRFSSRSLRSSTPLSRYFLSSSPSENKFEFHHFLSYTVTAELPTSAFTFVDAPQSLTSCADVWSHPCRAFVFFPLQRSRTSVGFSPSSHSIRPSPRRWFSSVNLCALRASFGSIASSCSSPVGPDHSSLTAVAITRAVRCFPSHSAPFPPSSSCDLLSASSPSHASLPACSASASSSSPPSRARPTVCLYVPRTHSPRPPRSVGSAASPSSGGPRVSQSEGTPSGPVDSPLSPTSRGSCSYSTPSVSCPGGLLLSLPSVSPVSLSTSLRHFLVSYTSPFPARSLPLIFVDAGLSLASDASLHAARPVGLSQEHRETCASALGSLIDTAVASNAVAQTSCECRPRGLPIVYSPRLVPPSFPRNHCLQPQKLGRLFSFLTHPSGASNLRTPESGVTKTWEAREAEIAKATSGVEGSHEFRWDYVTVHSDLRPKRLNSDHPVTKAGIGVGENRGREKNGEDGRPSEAGCEKSTSPSHALSPSASVPHGPVDATRQNGCGRDDPPRCTHPAGVQVTAGNELNRNPLLAGSHDQHMDSTRATLGTSVSSCFSLFSPIHDADVTRAWLQVVHAPEYVCAASAAVLSE----EE-----ERKIGFPVTKGYADKSLAEVSSTVLGTWLAFHFGLACVVGGGT--HHAKTDSGGKFCVFNDVAVAAALALKQGIAERILILDLDVHQGDGTAEIFSNEPRVKTVSIHCED--NFPFP-----------KAQSDVDIGLPAGTGDEVYLRQLNEVG 1C3P Chain:A ((19-239)) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNHPLKIPRVSLLLRFKD-------AMNLIDEKELIKSRP---ATKEELLLFHTEDYINTLMEAERCQCVPKGAREKYNIGGYENPVSYAMFTGSSLATGSTVQAIEEFLKGNV--AFNPAGGMHHAFKSRANGFCYINNPAVGIEYLRK-KGFKRILYIDLDAHHCDGVQEAFYDTDQVFVLSLHQSPEYAFPFEKGFLEEIGEGKGKGYNLNIPLPKGLNDNEFLFALEKSL

General information: TITO was launched using: RESULT: Template: 1C3P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 900 -34616 -38.46 -175.71 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.55 3D Compatibility (PKB) : -38.46 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.338

(partial model without unconserved sides chains): PDB file : Tito_1C3P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1C3P-query.scw PDB file : Tito_Scwrl_1C3P.pdb: