Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -VANTDTDTNTNISI-----------NPAQPARRV--------FKIDGVDFTPLDTDCLIRICKGDK-----TIHAKFAPAGTE--FDWYLDDRLTVLRLRSDCSVISGYVPKPW--KVQGDKVSALPDDLSIVLAKWK 1G3P Chain:? ((92-217)) EYGDTPIPGYTYINPLDGTYPPGTEQNPANPNPSLEESQPLNTFMFQNNRFRNRQGALTVYTGTVTQGTDPVKTYYQYTPVSSKAMYDAYWNGKF------RDCAFHSGFNEDIFVCEYQGQSSDLPQPPVNA------

General information: TITO was launched using: RESULT: Template: 1G3P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 339 18754 55.32 193.34 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 55.32 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.105

(partial model without unconserved sides chains): PDB file : Tito_1G3P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1G3P-query.scw PDB file : Tito_Scwrl_1G3P.pdb: