Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKEKMFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGENIVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLN-----LDSVDIVTGFNIPLLVELISSYDSKINLEE----IVHNAQNSLFNVKQQLNVEEEEDLCL 3IPR Chain:D ((1-138)) -------MLGIVIATHGALSDGAKDAATVIMGA--TENIETVNLNSGDDVQALGGQIKTAIENV-QQGDGVLVMVDLLSASPYNQAVLVINELEPALQKKIFVVSGTNLPMVLEAINHQLLGTPIAEAAQAIVAQGKESVQAWDISMT---------

General information: TITO was launched using: RESULT: Template: 3IPR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 631 -51036 -80.88 -395.62 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain D : 0.71 3D Compatibility (PKB) : -80.88 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.544

(partial model without unconserved sides chains): PDB file : Tito_3IPR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IPR-query.scw PDB file : Tito_Scwrl_3IPR.pdb: