Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLTTPVELVGEHVILKPLDVTQAEALKEAVCDGELYNLWYTRVPRPEQMTAEIERRLDLQKSGSMLPFYIEDRKTGRALGMTTLMHIEEAHRRVEIGSTWYRKSAQRTPVNTECKKLLLAHAFETLNCIAVELRTSSLNVQSQAAIVRLGAKLDGVLRSHQIVKDDILRDTHVYSILKHEWPAVRQNLEWLLNKPR 1YRE Chain:A ((13-195)) ----LPITLQRGALRLEPLVEADIPELVSLAEANREALQYMDGPTRPDWYRQSLAEQREGR------ALPLAVRLGVQLVGTTRFAEFLPALPACEIGWTWLDQAQHGSGLNRMIKYLMLKHAFDNLRMVRVQLSTAASNLRAQGAIDKLGAQREGVLRNHRRLAGGRLDDTFVYSITDHEWPQVKAALEASF----

General information: TITO was launched using: RESULT: Template: 1YRE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 840 -69974 -83.30 -382.37 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -83.30 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.408

(partial model without unconserved sides chains): PDB file : Tito_1YRE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YRE-query.scw PDB file : Tito_Scwrl_1YRE.pdb: