Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYDEECPIMANDNHNQVLDEHTEVVVEGDKASAKRARKVKPKTSDVGSTASLFGIAPYQPKKNEEYMSEGQLEHFRQILQTWKAELMSEVDRTLNTMQDESTALPDVNDRATQEEEFAIELRTRDRERKLIRKIEQSLEAIKNEDYGFCETCGIEIGLRRLEARPTATLCIDCKTLAEIKEKQNNG 4IJJ Chain:B ((12-132)) -------------------------------------------------------------PDAAYMDEAQQDFFRDLLLRQRQELQARIEGEFGELRD-LERPSDEADLASREEQRQWQLRLLEREKKLLDKIDEALERLARGDYGWCQETGEPIGLRRLLLRPTATLCIEAKERQEKRERH---

General information: TITO was launched using: RESULT: Template: 4IJJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 285 -20974 -73.59 -173.34 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.72 3D Compatibility (PKB) : -73.59 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.613

(partial model without unconserved sides chains): PDB file : Tito_4IJJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4IJJ-query.scw PDB file : Tito_Scwrl_4IJJ.pdb: